CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Each cell in a plant, animal, or person contains millions, or even billions, of DNA base pairs—molecules connected by hydrogen bonds that are the building blocks of DNA. These base pairs collectively ...

C-G base pairs in the DNA structure require more energy to break these bonds. Therefore, a higher abundance of C-G base pairs in the DNA structure increases the melting temperature. Divalent Cations ...

New work shows that physical folding of the genome to control genes located far away may have been a critical turning point for life on Earth. For evolutionary biologists, what most distinguishes the ...

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ingenious solution. A scientist examines a DNA (deoxyribonucleic acid) profile on ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was ...