The authors report a case of deficiency of the eighth component of complement in a young adult with a history of three episodes of meningitis; one of them proved to be meningococcal. The literature ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Question: I see a lot of PGA Tour players using 7-woods. I have one, too, and it’s terrific. Given that, should I look at a 9-wood to replace my 5-iron, which I have trouble hitting consistently?

Copyright: Published by Elsevier Ltd. The complement system is recognised as a protector against blood-borne pathogens and a controller of immune system and tissue ...

The authors have declared no conflicts of interest. Several diseases are related to complement involvement. In particular, its role is essential for the pathogenesis of several renal disease. On the ...

The complement system identifies and eliminates pathogens and dying cells, 3 pathways can activate the complement system—classical, lectin, and alternative—and their activation results in similar ...

The membrane attack complex (MAC or C5b-9) is an important effector of the immune system to kill invading microbes. MAC formation is initiated when complement enzymes on the bacterial surface convert ...

Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

1 Univ. Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France 2 Laboratoire d’Immunologie, Pôle de Biologie, CHU Grenoble Alpes, Grenoble, France Our immune system responds to infectious (PAMPs) and tissue ...