Integration of viral DNA into the host genome is an essential step in the replication cycle of human immunodeficiency virus 1 (HIV-1) and other retroviruses. The viral DNA, which is synthesized by ...
Latent HIV-1 reservoirs are established early during primary infection in CD4 + T cells and constitute a major barrier to HIV-1 eradication, even in the presence of highly active antiretroviral ...
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