A dose-response curve is the graphical representation of a dose-response relationship, the magnitude of response of an organism from exposure to drugs and chemical interactors. Usually, dose is ...

Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability ...

For patients with chronic-phase chronic myeloid leukemia (CML), a response-based dose-reduction strategy for ponatinib (Iclusig) may limit its toxicity while maintaining or improving efficacy, a ...

“For if one drinks much from a bottle marked ‘poison,’ it’s almost certain to disagree with one sooner or later.” —Lewis Carroll, “Alice’s Adventures in Wonderland” In the early 16th century, a Swiss ...

Phase II study of oxaliplatin, high-dose capecitabine, and sorafenib in patients with advanced pancreatic cancer. Background: Chemoradiation for anal cancer yields effective tumor control, but is ...