The transient receptor potential (TRP) ion channels comprise a diverse superfamily of cation channels that play pivotal roles in sensory transduction, enabling organisms to detect a wide range of ...

After the onset of painful peripheral stimuli, nociceptive neurons are activated and instigate a cascade of neuronal firings that transmit along the axons of the primary afferent fibers toward nerve ...

The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these potential risks. Now, ...