Final, 247th participant randomized and commences treatment in Actinogen’s XanaMIA pivotal phase 2b/3 Alzheimer’s trial

Topline final safety and efficacy results for the full 36 weeks of treatment from all participants will be available in ...
BMJ Open

Prospective randomised controlled trial of the use of nasogastric tubes in patients with adhesive small bowel obstruction (ASBO): protocol for the NASBO study

Introduction Nasogastric tubes (NGTs) are standard practice in the management of adhesive small bowel obstruction (ASBO). Their insertion can be associated with significant patient discomfort and ...
Open Heart

Mineralocorticoid receptor antagonists for acute myocardial infarction: a systematic review and meta-analysis of randomised controlled trials

Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains ...
News Medical

Randomized clinical food trials: Best clinical practice, quality management & data processing

Thought LeadersAoife Hayes, Kevin O'Regan & Julie ScanlonClinical Trials Assitant, Operations Manager & Quality Assurance ManagerAtlantia Clinical Trials Food clinical trials may not be as familiar to ...
STAT

Keeping pregnant participants out of medical research is more dangerous than including them

“Well, we don’t have as much evidence as we would like on steroid use during pregnancy,” the obstetrician warned my co-author, Natalia Emanuel, as she wrote a prescription for inhaled corticosteroids ...
JSTOR Daily

Can Randomized Controlled Trials Be Remedied?

Daedalus, Vol. 154, No. 2, The Ethics of Social Research: Perspectives from the Study of the Middle East & North Africa (Spring 2025), pp. 157-168 (12 pages) As the Middle East and North Africa (MENA) ...
Open Heart

Pooled randomised QUARTET trials assessing effectiveness of a single pill for hypertension

Background Hypertension is a major cause of premature death worldwide, controlled by only one in five adults. Two trials ...