James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

In a finding that may one day provide treatments for central nervous system diseases such as amyotrophic lateral sclerosis (ALS), researchers in Japan may have discovered a way to smuggle molecules ...

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact. These ...

New data suggest motor function improves with amifampridine. New phase 2 data for the spinal muscular atrophy (SMA) therapy amifampridine (Ruzurgi) suggests the drug is safe and effective at improving ...

ORLANDO, Fla.--(BUSINESS WIRE)--In a recent study published in Biomaterials, a team of researchers led by Hesperos Chief Scientist Dr. J. Hickman established a significant finding to better understand ...

Frog neuromuscular junction fly-through. Shown in red is a large muscle fiber (diameter 50 micrometers) that is innervated by a myelinated axon colored in white. The interface between muscle and axon ...

New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD). In preclinical DMD mouse models, investigators demonstrated ...

Ocular myasthenia gravis is an autoimmune condition affecting the muscles surrounding and involving the eyes. Symptoms can include double vision, droopy eyelids, and more. Ocular myasthenia gravis ...

Neurology encompasses a vast spectrum of disorders that affect the central and peripheral nervous systems, with neuromuscular diseases representing a significant subgroup. These disorders include ...