Mitophagy describes the process by which damaged or dysfunctional mitochondria are selectively degraded and recycled by the cell. The molecular mechanisms that regulate mitophagy include key proteins ...

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway. Mitophagy is an essential part of mitochondrial quality control and plays ...

Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide ...

Researchers at WEHI in collaboration with a team at the University of Vienna have discovered two proteins that act as regulators for mitophagy. Mitophagy is the process cells use to recycle damaged ...

New research highlights middle age as a pivotal period for brain health, with significant changes in how cells remove damaged mitochondria. Defects in this recycling process have been linked to ...

Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...

A month of Urolithin A supplementation restored youthful energy metabolism in immune cells, hinting at a safe nutritional strategy to counter immune aging and improve resilience to infections. Study: ...

There are currently dozens of different molecules and compounds at trial stage, as scientists across the globe search for the knockout anti-aging drug, but most have a common thread: finding a way to ...