Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Measuring membrane thickness was previously only possible in artificial membranes—now scientists can do it inside intact cells, providing crucial context for understanding how cells work.

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...

Cells do more than carry out chemical reactions. New theoretical work suggests they may also generate usable electrical ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

Study data indicate that membrane perforation registers as danger and is sufficient to launch type 2 immune pathways in the airway epithelium. The authors argue that many otherwise unrelated allergens ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the University of Massachusetts Amherst, could have applications beyond ...