An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches. For people with tooth decay, drinking a cold beverage can be agony.

Odontoblasts, the cells that form a tooth's dentin, have a newly discovered function: Sensing cold, which can trigger pain in teeth; but scientists have also found a way to block the pathway to ...

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp ...

There’s a special type of pain when something that is just too cold hits your teeth. This pain is so visceral, medical textbooks written throughout human history have recounted tales of a “tooth worm, ...

Researchers figured out how a jolt of discomfort gets from the damaged outside of your tooth to the nerves inside it. By Veronique Greenwood There’s nothing quite like the peculiar, bone-jarring ...

For people with tooth decay, drinking a cold beverage can be agony. "It's a unique kind of pain," says David Clapham, vice president and chief scientific officer of the Howard Hughes Medical Institute ...