Fragment-based drug design (FBDD) has led to a revolution in contemporary drug discovery, facilitating a bottom-up approach to the identification and evolution of bioactive small molecules into viable ...
Since the successful production of humanized antibodies in the 1980s, antibody-based medications have become increasingly essential in clinical treatment, taking advantage of their low immunogenicity ...
Developing new pharmaceuticals is a complex and costly process that requires innovation and efficiency. High-throughput immunoassays (HTIs) are an emerging technology poised to accelerate the drug ...
The Echo® MS+ system unlocks enhanced high-throughput screening capability by bringing acoustic ejection mass spectrometry (AEMS) approaches to the SCIEX ZenoTOF 7600 system. FRAMINGHAM, ...
To battle this epidemic, the National Institutes of Health (NIH) launched the Helping to End Addiction Long-term (HEAL) Initiative in 2018. As part of this effort, scientists at the NIH National ...
Physiochemical properties such as solubility and dissolution rate play a crucial role when it comes to the therapeutic efficacy of oral drug formulations. According to the Biopharmaceutical ...
Live-cell imaging, integrated with AI/ML, enhances phenotypic screening, improving drug discovery and lead optimization. European companies are pioneering live-cell imaging technologies, advancing in ...
This rapid screening process identified an iridium-based antibiotic candidate that shows promise in human cells to kill bacteria while remaining nontoxic.
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