News Medical on MSN
Brain-specific enzyme drives branching and extension of O-mannose glycans
Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function. These ...
AZoLifeSciences on MSN
Understanding the complex biosynthetic pathway of O-mannose glycans in the brain
Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...
Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex ...
CD BioGlyco's experience in this field demonstrates that through meticulous fine-tuning of reaction conditions, chemical methods can achieve both efficient and broad-spectrum glycan release while ...
A type of glycan called “N-glycan” is usually extended by the actions of several enzymes (glycosyltransferases). The terminal sugar “sialic acid” increases protein stability in blood. Once B4GALNT3 ...
CD BioGlyco leverages its state-of-the-art platform and years of experience to deliver precise and consistent modifications to your antibody glycans. Researchers can now access homogeneous glycoforms ...
New automated N-glycan profiling web app shaves days off of data interpretations for glycobiologists
The first automated, web-based application that enables routine use of enzymatic digestions to improve N-glycan structural analyses, GlycanAnalyzer, has been released from New England Biolabs (NEB).
Glycans, or structures of sugar molecules in our cells, can be measured by mass spectrometry. One important use is that the structures can indicate different forms of cancer in the cells. However, the ...
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