Molecular docking studies represent a cornerstone in modern drug discovery by providing detailed insights into the specific interactions between bioactive compounds and target enzymes. This ...

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have ...

Recent evidence suggests that natural products are much more than simply agents of “microbial warfare” and actually play critical roles in bacterial pathogenesis and communication. In particular, ...

In the context of the coronavirus disease 2019 (COVID-19) pandemic, with over 3.5 million deaths and counting as of June 9, 2021, the development of effective antivirals remains essential. This ...

Regulation of Oct4 signaling on tumorigenesis and modulation of wnt/β-catenin and TGF-β signal pathways in hepatocellular carcinoma cells. Efficacy of vemurafenib (V), a selective V600Eb-raf inhibitor ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

Scientists have long assumed that once the smooth cartilage in a damaged knee wears away, the body has little chance of restoring it. A new line of research is challenging that assumption by showing ...