There exists a unique and clinically relevant time course of urinary drug delivery for a loop diuretic at which the natriuretic response is optimized. This rate of drug delivery resides on the steep ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

A magnifying glass. It indicates, "Click to perform a search". A magnifying glass. It indicates, "Click to perform a search". SILVER SPRING, Md., Feb. 25, 2019 /PRNewswire/ -- "How a drug is absorbed ...

Membrane proteins are the target of most drugs currently on the market due to their relationship with the vast majority of diseases they are designed to treat. Drug activity depends on numerous ...

The effort to increase the number of druggable targets has coincided with a substantial expansion of the chemical property space in which new drug candidates can reside. As a consequence, contemporary ...

In this interview, Karl Box from Pion outlines the benefits of particle drift analysis using flux tools and how this can be used to enhance oral drug absorption in pharmaceutical research. Pion's ...

Stability is a critical factor in drug formulation, with implications for product quality, lifecycle management, and ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...