A genetic breakthrough reveals why mental health conditions often occur together. New research identifies five disorder groups sharing DNA patterns.

Mutations (blue) in U2 snRNA cause a neurodevelopmental disorder about one-fifth as common as the RNU4-2/ReNU disorder, which is linked to mutations (orange) in U4 snRNA. snRNAs are shown in black, ...

A global research collaboration has revealed a hidden cause of a rare intellectual disorder associated with severe language delay, epileptic seizures, motor impairment and brain abnormalities. The ...

Researchers have deepened our understanding of two of the five members of the CDKL family of genes, CDKL2 and CDKL1. They show that variants in these genes can lead to neurodevelopmental conditions, ...

Paternal use of the anti-seizure medication valproate during spermatogenesis was not associated with a risk of congenital malformations or neurodevelopmental disorders in offspring, an observational ...

Children with neurodevelopmental disorders report congenital abnormalities, such as defects of the heart and/or urinary tract, at least ten times more frequent compared to other children. This is one ...

Microglia are shown in red, and CD11c-positive cells in green. Scale bar = 100 µm. A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism ...

For babies born with alternative hemiplegia of childhood (AHC), an extremely rare and severe neurodevelopmental disorder, there may be no obvious symptoms for several months. Then the attacks begin: ...

Scientists have identified rare mutations in a single gene that may directly begin causing mental illness as early as childhood, a finding that could change how doctors diagnose and treat psychiatric ...

A research group led by the University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial role in protecting the developing brain from harmful mutations. The study found that a ...