UNIVERSITY PARK, Pa. -- L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study. The research ...

For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin ...

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

A little extra calcium is a good thing, to help maintain healthy bones and muscles. However, too much calcium in your neurons could be an underlying cause of memory loss for those afflicted with ...

Zalicus Initiates the First of Two Phase 2a Studies with Z160, a First-in-Class, Oral, State-Dependent, Selective N-type Calcium Channel Blocker, for the Treatment of Chronic Neuropathic Pain (NASDAQ: ...

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

Ethosuximide does not demonstrate efficacy over placebo for the treatment of irritable bowel syndrome-related abdominal pain and has limited tolerability.

Heart disease medication plays a critical role in managing and preventing cardiovascular conditions. Understanding the various types, their mechanisms, and how they work can help people make informed ...

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have ...